Made with non-GMO ingredients.

Manufactured in a GMP Registered Facility in the USA

  • Product Size: 120 vegetarian capsules
  • Servings Per Container: 30

Copyright © Adaptogen Research. All Rights Reserved.

HistaCalm also contains quercetin, nettle leaf and vitamin C, all of which have long histories of use in helping to support immune balance during the allergy season. Additionally, bicarbonate salts are included for their role in maintaining normal histamine metabolism.


*These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. The information contained herein is for informational purposes only and does not establish a doctor-patient relationship. Please be sure to consult your physician before taking this or any other product. Consult your physician for any health problems.

  • Tinofend® is an extract from the plant Tinospora cordifolia, which has been used since the early 1900s in Ayurvedic medicine for its immune-modulating action. Tinofend® contains a complex of polysaccharides and polyphenols that has been shown to regulate key immune mediators and stimulate the activity of macrophages—specialized cells that are a primary part of the immune system.


  • Additional Highlights:   Vitamin C, quercetin, and nettles – All three provide antioxidant benefits and help support the immune system.


  • Vitamin C:-  One of the most well-known and widely studied nutrients of our day, vitamin C (ascorbic acid) is a water-soluble vitamin with many functions in the body. Besides its antioxidant and immune-supportive roles, it is necessary for the body to make collagen in bones, cartilage, muscle, and blood vessels. It is a naturally occurring compound found in many plant foods, most notably citrus fruits, berries, pineapple, bell peppers, and broccoli.


  • Quercetin:- has been called “king of the flavonoids” because of its powerful antioxidant properties and its ability to promote a healthy response to inflammation. It is found in many foods that are recognized for their health benefits, such as red onions, apples, olive oil, dark berries and grapes, capers, salad greens and culinary herbs, such as dill, cilantro, watercress, and radicchio. (Quercetin contributes to the richly colored pigments in these foods.)


  • Nettles:- (a.k.a. “stinging nettle”) is a perennial flowering plant which has been employed throughout the ages and across the globe for a wide variety of purposes. Documentation points to its use in ancient Egypt, ancient Greece, and among native peoples in North America. Nettle has been consumed directly, or made into soup or tea. Its high content of vitamin C and iron underlies its immune-supporting effects. Nettle has traditionally been used for supporting respiratory and joint health. It is also a compound with natural abilities to help balance the body’s inflammatory response.

HistaCalm 

HistaCalm is a synergistic blend of nutrients that provides natural support to help balance the immune response during allergy season. It features Tinofend®, a patented and clinically researched extract derived from the plant Tinospora cordifolia, which has been shown to regulate key immune mediators and support the activity of macrophages. Tinofend® supports the immune response by promoting a balance of phagocytic white blood cells and eosinophils.

Adaptogen Research, HisaCalm